STUDY & CORRESPONDENCEAugust 2026 · Endocrine Practice
Evidence deserves a closer look.
Read the five-study network meta-analysis alongside a forthcoming letter questioning trial identification, omitted safety data, and rare-event rankings. Acceptance of the letter is reported by its author.
The randomized Phase III trial compared weekly Pegpesen with daily somatropin in treatment-naïve children with GHD. The study met its prespecified non-inferiority criterion for growth velocity.