Explore the science

A closer look
at the science
of growth.

Explore inpegsomatropin, clinical evidence,
and the questions shaping research.

AI-generated conceptual illustration
STUDY & CORRESPONDENCEAugust 2026 · Endocrine Practice

Evidence deserves a closer look.

Read the five-study network meta-analysis alongside a forthcoming letter questioning trial identification, omitted safety data, and rare-event rankings. Acceptance of the letter is reported by its author.

Read the analysis →

Research watch / September 2026

More from the research library.

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CONFERENCE ABSTRACTENDO 2026

Exploring non-GHD short stature

A 52-week Phase II basket trial in 78 children reports findings across ISS, SGA, and Turner syndrome.

Read the preliminary findings ↗
MODEL-BASED RESEARCHMarch 2026 issue

A different lens on weekly dosing

The population PK/PD study explores dose titration and weight bands through simulation.

Explore the modeling paper ↗
Once weeklySubcutaneous administration
3+ yearsChina label: pediatric GHD
391Children in the Phase III trial
52 weeksPivotal comparison with daily GH

The pivotal study

A weekly regimen.
A 52-week comparison.

The randomized Phase III trial compared weekly Pegpesen with daily somatropin in treatment-naïve children with GHD. The study met its prespecified non-inferiority criterion for growth velocity.

Study design, outcomes & safety ↗

Product reference

Meet Pegpesen.

Inpegsomatropin injection. Explore composition, presentations, local product information, and the delivery system.

View product information
Pegpesen packaging and injection device, official Amoytop product image
Official Amoytop product image ↗